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Current Status of Multicenter Cancer Cohort Study with Biological Materials Bank in Korea.
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Keun Young Yoo, Hai Rim Shin, Song Hun Chang, Jung Myung Choi, Chang Yup Kim, Kun Sei Lee, Won Jin Lee, Dae Hee Kang, Bu Ok Lee, Duck Hee Lee, Sue Kyung Park, Joo Hon Sung, Yeong Su Ju, Dae Sung Kim, Jong Won Kang, Soo Hun Cho
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Korean J Epidemiol. 1998;20(2):275-278.
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 Abstract
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Abstract
This cohort study is a collaborative effort of 8 institutions. The goal is to establish a large scale cohort that can be followed for 10 or more years to assess the relationship between life-styles and cancer occurrence, and to evaluate the role of environmental exposures in the development of six major sites of cancers(stomach, liver, lung, colorectum, uterine cervix and female breast) in the rural population. Since 1993, 11,304 men and women aged over 35 living in four areas have been recruited. The number of target population is 30,000 persons, which is expected to be successfully recruited until 1999. Each subject has completed a detailed questionnaire on general life-styles, reproductive factors, and agricultural chemical exposures through the interview. Anthropometric measurements with body fat composition and the routine clinical laboratories were examined. For the cancer-free cohort, physical examination by the physicians and serologic tests for hepatitis markers, some tumor markers, and lipid profile have been done, but not all. In order to provide an opportunity to incorporate barious biomarkers of exposure and effect as well as genetic susceptibility, a biologic tissue bank has been established from blood and urine sample(plasma, WBC buffy-coat, RBC clots, and urine supernatant) stored at-70degrees C.
Re-examination of changes in exposere to risk factors will be done periodically. Disease occurrence will be ascertained by the active(mainly through diagnosis by physicians) and the passive surveillance(through both death certificate and screening of medical utilization records).
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Summary
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Avoidable' causes of death in Korea 1982-1991.
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Yun Mi Song, Chang Yup Kim
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Korean J Epidemiol. ;15(2):160-172.
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Abstract
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Abstract
For the basic study of the impact of qulaity of health care services on the health status of population, mortality from potentially avoidable causes of death in Korea for the period of 1982-1991 was analyzed, based on a list which was revised from the original version by Rutstein et al(1976). The conditions listed were suggested to serve as negative indicatiors of the quality care services provided to target populations. Data for analysis were from the Annual Report on the Causes of Death Statistics 1982-1991 by the Korea National Statistical Office.
In 1991, 24.9% of death were classified as avoidable. There was large decline for avoidable causes of death by 37.4% of 1982. Mortality from all other causes, however, showed a smaller decline of 24.6%. Mortality from avoidable causes decreased more remarkably for male than female.
As for age groups, decrease in avoidable deaths was more prominent than unavoidable deaths in the population of age more than 65 years, while in younger age groups deaths due to unavoidable causes were more sharply decreased.
The most rapidly declined cause of mortality was acute respiratory disease, and nutritional deficiency, pneumonia and influenza, meningitis, and hypertension showed similar decreasing tendencies. Among causes, mortality from epilepsy and rheumatic diseases was not so markedly lessened.
In Korea, compared to other developed countries, the rate of decrease in deaths from avoidable causes was rather lower. Additional analyses, however, should be performed for more valid information on the features of mortality patterns, offer validation of existing mortaling data. In the consecutive studies, the change of health services factors would be correlated with mortality changes.
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